Pathologies of the ocular surface

The ocular surface plays a fundamental role in patient comfort and vision. Densmore Laboratory develops innovative formulas to improve its conditions.


Ocular surface: an ecosystem to preserve

The ocular surface is a complex environment that provides the interface between the eye and the external environment: our visual perception is due to the penetration of light through the cornea and the focus of the image on the retina1. The tear film ensures the correct transmission of the image. Therefore, any deficiency in its structure may have consequences on the quality of perception. In addition, the ocular surface is optically effective provided that the cornea, conjunctiva and eyelids are not disturbed by pathologies1,2.


Ocular surface disorders

The ocular surface is most often affected by problems with transmitting visual information to the retina. The symptoms are varied: redness, tearing, decreased visual acuity, feeling of graininess or burning, etc. They may be the consequence of degenerative, immunological, allergic, infectious or inflammatory pathologies such as dry eye1. The ophthalmologist is the preferred contact for establishing a diagnosis and defining the best care1,2.


The impact of the environment and lifestyles

The prevalence of ocular surface disorders has been increasing for several decades2. The factors involved are numerous: environment (air pollution, high temperature, low humidity, inadequate ventilation), equipment (air conditioning, exposure to screens and LEDs, etc.), chemical aggressions (aldehydes, carbon monoxide, preservatives, etc.), certain dietary deficiencies or the wearing of contact lenses2.

To preserve the quality of life for patients, the Densmore laboratory teams work to identify effective molecules and to develop ophthalmic solutions.


References:
1. Doan S, Dry eyes: from the clinic to treatment. – Med’com, 2008.
2. Pisella PJ, Baudouin C, Hoang-Xuan T, SFO Report: Ocular surface. – Elsevier-Masson, 2015.